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Downsizing follows the adventures of Paul Safranek (Matt Damon), an everyman from Omaha who, along with his wife Audrey (Kristen Wiig), dreams of a better life. As the world faces an overpopulation crisis, scientists develop a radical solution that can shrink humans to five inches tall. People soon discover how much further money goes in a smaller world, and with the promise of a lavish lifestyle beyond their wildest imaginations, Paul and Audrey decide to risk the controversial procedure and embark upon an adventure that will change their lives forever.